Every Cure
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| Founded | 2022 |
|---|---|
| Founders | David Fajgenbaum, Grant Mitchell, Tracey Sikora |
| Type | Nonprofit organization |
| Focus | Drug repurposing |
| Location |
|
Area served | Global |
President | David Fajgenbaum |
| Website | everycure |
Every Cure is an American nonprofit organization established in 2022 to identify and advance repurposed drugs for people battling diseases with no approved treatments.[1] The organization applies artificial intelligence and computational methods to identify potential matches between existing FDA-approved drugs and known diseases.[2]
History
Every Cure was co-founded in 2022 by physician-scientist David Fajgenbaum, Grant Mitchell, and Tracey Sikora.[1] Its origins trace to Fajgenbaum’s personal experience with Castleman disease, a rare inflammatory condition that nearly killed him five times. While a medical student in 2010, Fajgenbaum became critically ill; after being told there were no treatment options for his disease, he began investigating possible treatments.[3] He identified the drug sirolimus, previously approved as an immunosuppressant, as a possible therapy for his condition. The treatment placed him into long-term remission, an experience that influenced the creation of Every Cure.[4]
Activities
Every Cure identifies opportunities for drug repurposing, evaluates and prioritizes these opportunities, and builds scientific evidence to get treatments to patients in need. The organization describes its approach as “computational pharmacophenomics,” which involves analyzing biomedical data to assess the potential of all FDA-approved drugs across all recognized diseases.[5] According to the Every Cure website, their mission is "to save and improve lives by repurposing drugs" and their vision is to create a world where every drug is used to treat every disease it can.
The group uses AI-based tools, including knowledge graph integration of biomedical datasets, large language models to evaluate scientific evidence, and analyses of real-world data such as electronic health records.[6] Candidate drug–disease matches are reviewed by medical experts and an independent scientific advisory council.[6]
Every Cure collaborates with clinical research organizations, academic labs, and patient advocacy groups to generate preclinical and clinical evidence. The organization also works to maximize patient access by assisting with regulatory approvals, updating treatment guidelines, educating clinicians, and conducting outreach campaigns.[6]
Recognition
The organization has been profiled by media outlets including The New York Times,[4] The Wall Street Journal,[7] The New Yorker,[8] USA Today,[9] and CBS Evening News.[10]
Awards and recognition include being named to the TIME100 Health list,[11] inclusion in the TED Audacious Project,[12] and the Newsweek AI Impact Award.[13]
References
- ↑ 1.0 1.1 "Every Cure". MIT Solve. Retrieved 28 August 2025.
- ↑ "About Every Cure". Every Cure. Retrieved 28 August 2025.
- ↑ Fajgenbaum, David (2019). Chasing My Cure: A Doctor's Race to Turn Hope into Action. Ballantine Books. ISBN 978-1524799618.
- ↑ 4.0 4.1 Kolata, Gina (March 20, 2025). "Can A.I. Find Cures for Untreatable Diseases Using Drugs We Already Have?". The New York Times.
- ↑ Fajgenbaum, D. C.; Nijim, S.; Mitchell, G.; Macak, M.; Bizon, C.; Tropsha, A.; Koslicki, D. (2024). "Computational pharmacophenomics: a systematic approach to drug repurposing". The Lancet Healthy Longevity. 12 (2): e94–e96. doi:10.1016/S2352-3026(24)00278-3.
- ↑ 6.0 6.1 6.2 "Our Work". Every Cure. Retrieved 28 August 2025.
- ↑ "This Doctor Found His Own Miracle Drug. Now He Wants to Do It for Others". The Wall Street Journal. February 12, 2025.
- ↑ "Can A.I. Find Cures for Untreatable Diseases Using Drugs We Already Have?". The New Yorker. April 2025.
- ↑ "Clinton initiative adds Every Cure to expand use of generic drugs for rare diseases". USA Today. September 18, 2022.
- ↑ "Autism families push for more research into repurposed medicine". CBS News. March 2025.
- ↑ "TIME100 Health 2025". Time. 2025.
- ↑ "Every Cure receives $60 million commitment through TED's Audacious Project". Every Cure. 2024.
- ↑ "Newsweek's AI Impact Awards 2025". Newsweek. 2025.
External links
This article "Every Cure" is from Wikipedia. The list of its authors can be seen in its historical. Articles taken from Draft Namespace on Wikipedia could be accessed on Wikipedia's Draft Namespace.