Lhasa Limited

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Lhasa Limited
Not-for-profit educational charity
IndustrySoftware, Chemical safety
Founded1983
FoundersPeter Johnson, Philip Judson
HeadquartersLeeds, United Kingdom
Area served
Worldwide
Key people
Chris Barber (CEO)
ProductsDerek Nexus, Sarah Nexus, Meteor Nexus, Zeneth, Vitic, Mirabilis, Kaptis, Acrostic, LCDB
Number of employees
200
Websitewww.lhasalimited.org

Lhasa Limited is a UK-based not-for-profit educational charity founded in 1983,[1][2] specialising in the development of software that supports decision-making in chemical safety assessments.[3] The company originated from the Logic and Heuristics Applied to Synthetic Analysis (LHASA) project developed at Harvard University and later the University of Leeds.[4]

History

Lhasa Limited was established by Dr Peter Johnson and Dr Philip Judson, evolving from the original LHASA project at Harvard and the University of Leeds.[5] Initially based within the University of Leeds, Dr Peter Johnson built a team focused on expert systems for chemical synthesis and toxicology prediction.[6]

The organisation was set up as a not-for-profit entity and registered as an educational charity, with the goal of improving chemical safety through shared knowledge and predictive software.[7]

Software

Lhasa Limited develops software used in chemical safety assessment, including Derek Nexus[8], Sarah Nexus[9], Meteor Nexus[10] and Zeneth.[11]

Key milestones and achievements

Lhasa Limited received the Queen’s Award for Enterprise: Innovation twice, first in 2016 for Derek Nexus and again in 2017 for Sarah Nexus.[12][13]

References

  1. "LHASA LIMITED". Register of Charities. Retrieved 15 August 2025.
  2. "Lhasa Limited annual report and consolidated financial statements". Register of Charities. Retrieved 15 August 2025.
  3. "Our solutions". Lhasa Limited. Retrieved 14 August 2025.
  4. Pensak, David; Corey, E.J. (1 June 1977). "LHASA—Logic and Heuristics Applied to Synthetic Analysis". Computer-Assisted Organic Synthesis. ACS Symposium Series. Vol. 61. American Chemical Society. pp. 1–19. doi:10.1021/bk-1977-0061.ch001. ISBN 978-0-8412-0394-5. Retrieved 18 August 2025.
  5. "Chapter 4. International Repercussions of the Harvard LHASA Project". Knowledge-based Expert Systems in Chemistry. Theoretical and Computational Chemistry Series. 2019. pp. 39–45. doi:10.1039/9781788016186-00039. ISBN 978-1-78801-471-7.
  6. "About Us - Keymodule". Keymodule. Archived from the original on 2024-07-24. Retrieved 2025-08-13.
  7. "LHASA LIMITED". Register of Charities. Retrieved 18 August 2025.
  8. Judson, Philip (2009). Knowledge-based Expert Systems in Chemistry: Not Counting on Computers. Royal Society of Chemistry. ISBN 9780854041602. Retrieved 2025-11-21.
  9. Cayley, Alex N.; Foster, Robert S.; Brigo, Alessandro (2023). "Assessing the utility of common arguments used in expert review of in silico predictions as part of ICH M7 assessments". Regulatory Toxicology and Pharmacology. 144 105490. doi:10.1016/j.yrtph.2023.105490. PMID 37659712. Retrieved 2025-11-21.
  10. Marchant, Carol A.; Briggs, Katharine A.; Long, Anthony (2008). "In silico tools for sharing data and knowledge on toxicity and metabolism: Derek for Windows, Meteor, and Vitic". Toxicology Mechanisms and Methods. 18 (2–3): 177–187. doi:10.1080/15376510701857320. PMID 20020913.
  11. Hemingway, Rachel; Baertschi, Steven W.; Benstead, David (2024). "In Silico Prediction of Pharmaceutical Degradation Pathways: A Benchmarking Study Using the Software Program Zeneth". Organic Process Research and Development. 28 (3): 674–692. doi:10.1021/acs.oprd.3c00344. Retrieved 2025-11-21.
  12. "The Winners: Queen's Awards for Enterprise 2016". The Royal Household. Retrieved 2025-11-21.
  13. "Queen's Awards for Enterprise 2017". The Royal Household. 11 July 2017. Retrieved 2025-11-21.

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